Could a car that knows when you are stressed or ill save you from having an accident? Auto makers are stepping up efforts to find out.

A number of big car manufacturers are accelerating research into equipping vehicles with so-called biometric sensors that would keep tabs on a driver's vital health signs, including pulse, breathing and "skin conductance," aka sweaty palms. When that information is fed into the computers that manage a car's safety systems, it could enable a vehicle to better react to whatever challenges the road and traffic dish out.

Already, some Lexus models use in-cabin cameras and some Mercedes-Benz vehicles have steering sensors to detect drowsy-driving behavior. The cars sound a warning beep or flash a coffee-cup icon to suggest that it's time for a break. Separately, car makers and federal safety regulators are working on in-vehicle systems that could reliably detect when someone is too drunk to drive.

The new body monitors could, if a driving hazard appeared imminent, trigger the car's safety systems to tap the brakes, turn off a radio, block a cellphone from ringing or take other actions.

Sports car maker Ferrari SpA, for one, has filed a patent application that indicates the company is evaluating technology that would embed wireless electrodes in a car seat's headrest to monitor drivers' brain waves for stress as they pilot machines capable of roaring up to 200 miles per hour. Depending on what the sensors detect, the car might try to mitigate the driver's risk by cutting power to the motor or automatically stabilizing the vehicle.