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In The News

In The News

April 12 - Human Embryo Genetic Modification: Chinese Researchers Report Another Attempt At Controversial Procedure

Article: Cloning And Genetic Engineering

According to a paper detailing the findings of the experiments, published in the Journal of Assisted Reproduction and Genetics, the technique was performed on 45 fertilized, non-viable human eggs. The scientists were able to introduce a naturally occurring genetic mutation named CCR5 Δ32 into the embryos. This mutation, when present in humans, makes the T-cells, which are a subtype of white blood cells, immune to the HIV virus.

Of the 45 embryos injected with the RNA instructions during their one-cell stage, only 26 developed into eight-cell embryos and beyond. And, out of these, only four acquired the desired mutation. Editing human embryos is problematic because it could have long-term, unintended consequences. One such effect, wherein a surprising number of �off-target� mutations that act on other parts of the genome come into being, was visible in this particular study as well as the previous one carried out last year.

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